Cabazitaxel Injection

Cabazitaxel Injection
Cabazitaxel Injection
Product Code : 00
Product Description
Technical Details:
  • Trade Name: Jevtana
  • Ingredients: Cabazitaxel
  • Manufacturer: Sanofi
  • Type: Injection
  • Power: 60 mg/1.5 ml
  • Molecular Formula: C45H57NO14C3H6O
  • Molecular Weight: 894.01 (for the acetone solvate) / 835.93 (for the solvent free)
  • Solubility: Insoluble in water and soluble in alcohol.
  • Form: White to almost-white powder

JEVTANA (cabazitaxel) injection is an antineoplastic agent belonging to the taxane class that is for intravenous use. It is prepared by semi-synthesis with a precursor extracted from yew needles.

The chemical name of cabazitaxel is (2α,5β,7β,10β,13α)-4-acetoxy-13-({(2R,3S)-3[(tertbutoxycarbonyl) amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1-hydroxy-7,10-dimethoxy-9oxo-5,20-epoxytax-11-en-2-yl benzoate – propan-2-one (1:1).

Cabazitaxel injection is indicated in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer previously treated with a docetaxel-containing treatment regimen.

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